Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 4/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.53 |
| ▸ | GRM6 | O15303 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL11207143 | 1.00 | GRM8 (0.53) | GRM8GRM4GRM6L3MBTL1MEN1 | |
| SCHEMBL742437 | 0.91 | ACP3 (0.56) | GRM8GRM4GRM6L3MBTL1MEN1 | |
| SCHEMBL11057509 | 0.91 | ACP3 (0.56) | GRM8GRM4GRM6L3MBTL1MEN1 | |
| SCHEMBL5157317 | 0.91 | ACP3 (0.56) | GRM8GRM4GRM6L3MBTL1MEN1 | |
| SCHEMBL11207149 | 0.82 | MEN1 (0.48) | GRM8GRM4GRM6L3MBTL1MEN1 | |
| SCHEMBL11205688 | 0.82 | MEN1 (0.48) | GRM8GRM4GRM6L3MBTL1MEN1 | |
| SCHEMBL4430624 | 0.80 | GRM8 (0.56) | GRM8GRM4GRM6L3MBTL1KMO | |
| SCHEMBL8582041 | 0.80 | AKR1C3 (0.67) | GRM8GRM4L3MBTL1MEN1HPGD | |
| SCHEMBL3992888 | 0.80 | AKR1C3 (0.67) | GRM8GRM4L3MBTL1MEN1HPGD | |
| SCHEMBL307016 | 0.80 | AKR1C3 (0.67) | GRM8GRM4L3MBTL1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009722-B1 | OPTICALLY ACTIVE COMPLEX, ALANINE.RING-SUBSTITUTED MANDELIC ACID, AND THE METHOD FOR PRODUCING THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-03-02 | — | — | EP | claimed |
| EP-0009722-A1 | Optically active complex, alanine.Ring-substituted mandelic acid, and the method for producing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-04-16 | — | — | EP | claimed |