Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.67 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.67 |
| ▸ | ACP3 | P15309 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3992888 | 1.00 | AKR1C3 (0.67) | AKR1C3AKR1C2ACP3HPGDL3MBTL1 | |
| SCHEMBL8582041 | 1.00 | AKR1C3 (0.67) | AKR1C3AKR1C2ACP3HPGDL3MBTL1 | |
| SCHEMBL27474822 | 0.88 | L3MBTL1 (0.55) | AKR1C3AKR1C2ACP3HPGDL3MBTL1 | |
| SCHEMBL7733013 | 0.85 | ACP3 (0.54) | AKR1C3AKR1C2ACP3HPGDL3MBTL1 | |
| SCHEMBL10763187 | 0.85 | TSHR (0.54) | AKR1C3AKR1C2ACP3HPGDL3MBTL1 | |
| SCHEMBL2407166 | 0.85 | ALDH1A1 (0.54) | AKR1C3AKR1C2ACP3HPGDL3MBTL1 | |
| SCHEMBL30428765 | 0.85 | TSHR (0.54) | AKR1C3AKR1C2ACP3HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27290579 | 0.84 | L3MBTL1 (0.55) | AKR1C3AKR1C2ACP3HPGDL3MBTL1 | |
| SCHEMBL5861774 | 0.83 | ACP3 (0.58) | ACP3L3MBTL1TP53SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL10759838 | 0.83 | L3MBTL1 (0.53) | AKR1C3AKR1C2ACP3HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810001-B | Synthesis method of ropinirole hydrochloride intermediate 2-methyl-3-nitrophenylacetic acid | 深圳市第二人民医院 | 2022-04-01 | — | — | CN | claimed |
| CN-109810001-A | The synthetic method of ropinirole hydrochloride intermediate 2- methyl-3-nitrophenylacetic acid | 深圳市第二人民医院 | 2019-05-28 | — | — | CN | claimed |
| CN-108126656-A | For the modified activated carbon absorbent of benzene in Adsorption wastewater from chemical industry | 北京益清源环保科技有限公司 | 2018-06-08 | — | — | CN | claimed |
| CN-102070433-B | Preparation method for aryl acetic acid derivative | GUILIN NORMAL COLLEGE | 2013-03-27 | — | — | CN | claimed |
| EP-1282680-A1 | COMPOSITIONS COMPRISING CYCLODEXTRIN | THE PROCTER & GAMBLE COMPANY (US) | 2003-02-12 | — | — | EP | claimed |
| US-6503413-B2 | Polyalkylene polysiloxane, buffering agent, aqueous carrier | THE PROCTER & GAMBLE COMPANY | 2003-01-07 | — | — | US | claimed |
| EP-1255806-A1 | STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| US-20020011584-A1 | Stable, aqueous compositions for treating surfaces, especially fabrics | THE PROCTOR & GAMBLE COMPANY | 2002-01-31 | — | — | US | claimed |
| US-20020010154-A1 | Compositions comprising cyclodextrin | THE PROCTER & GAMBLE COMPANY | 2002-01-24 | — | — | US | claimed |
| WO-2001088076-A1 | COMPOSITIONS COMPRISING CYCLODEXTRIN | THE PROCTER & GAMBLE COMPANY (US) | 2001-11-22 | — | — | WO | claimed |
| WO-2001060961-A1 | STABLE, AQUEOUS COMPOSITIONS FOR TREATING SURFACES, ESPECIALLY FABRICS | THE PROCTER & GAMBLE COMPANY (US) | 2001-08-23 | — | — | WO | claimed |
| EP-0077662-B1 | PREPARATION OF NITROARYLACETIC ACID ESTERS AND DERIVATIVES THEREOF | ETHYL CORPORATION (US) | 1985-10-02 | — | — | EP | claimed |
| US-4499026-A | Nucleophilic substitution process | ETHYL CORPORATION (US) | 1985-02-12 | — | — | US | claimed |
| US-4476315-A | NITROARYLACETIC ACID ESTERS FROM NITROAROMATIC COMPOUNDS | ETHYL CORPORATION (US) | 1984-10-09 | — | — | US | claimed |
| EP-0077662-A1 | Preparation of nitroarylacetic acid esters and derivatives thereof | ETHYL CORPORATION (US) | 1983-04-27 | — | — | EP | claimed |
| CN-116023321-B | STING inhibitor prodrug and medical application thereof | 中国药科大学 | 2024-11-29 | — | — | CN | disclosed |
| CN-110621660-B | Purification method of ropinirole hydrochloride | 浙江华海立诚药业有限公司 | 2022-06-28 | — | — | CN | disclosed |
| US-4476315-A | NITROARYLACETIC ACID ESTERS FROM NITROAROMATIC COMPOUNDS | ETHYL CORPORATION (US) | 1984-10-09 | — | — | US | disclosed |
| EP-0113964-A1 | 4-Aminoalkyl-2(3H)-indolones | SMITHKLINE BECKMAN CORPORATION (US) | 1984-07-25 | — | — | EP | disclosed |
| EP-0077662-A1 | Preparation of nitroarylacetic acid esters and derivatives thereof | ETHYL CORPORATION (US) | 1983-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010154-A1 | Compositions comprising cyclodextrin | FFAR4, FRG1, FGB | AKR1C3 601/4885AKR1C2 519/4885ACP3 1605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.