Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 4/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.47 |
| ▸ | GRM6 | O15303 | 3/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205688 | 1.00 | MEN1 (0.48) | MEN1HPGDKMT2AL3MBTL1GRM8 | |
| Alanine SCHEMBL11207143 | 0.82 | GRM8 (0.53) | MEN1HPGDKMT2AL3MBTL1GRM8 | |
| D-Alanine SCHEMBL11205686 | 0.82 | GRM8 (0.53) | MEN1HPGDKMT2AL3MBTL1GRM8 | |
| SCHEMBL2353731 | 0.82 | ALDH1A1 (0.53) | MEN1HPGDKMT2AL3MBTL1GRM8 | |
| SCHEMBL2189277 | 0.80 | LMNA (0.57) | MEN1HPGDKMT2AL3MBTL1GRM8 | |
| SCHEMBL10532381 | 0.80 | LMNA (0.57) | MEN1HPGDKMT2AL3MBTL1GRM8 | |
| SCHEMBL4988811 | 0.75 | CYP2D6 (0.48) | MEN1KMT2AL3MBTL1GRM8GRM4 | |
| SCHEMBL27616191 | 0.75 | SMN1; SMN2 (0.58) | MEN1HPGDKMT2ALMNAALDH1A1 | |
| SCHEMBL5157317 | 0.75 | ACP3 (0.56) | MEN1HPGDKMT2AL3MBTL1GRM8 | |
| SCHEMBL742437 | 0.75 | ACP3 (0.56) | MEN1HPGDKMT2AL3MBTL1GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009722-B1 | OPTICALLY ACTIVE COMPLEX, ALANINE.RING-SUBSTITUTED MANDELIC ACID, AND THE METHOD FOR PRODUCING THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-03-02 | — | — | EP | claimed |
| EP-0009722-A1 | Optically active complex, alanine.Ring-substituted mandelic acid, and the method for producing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-04-16 | — | — | EP | claimed |
| EP-0009722-B1 | OPTICALLY ACTIVE COMPLEX, ALANINE.RING-SUBSTITUTED MANDELIC ACID, AND THE METHOD FOR PRODUCING THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-03-02 | — | — | EP | disclosed |
| EP-0009722-A1 | Optically active complex, alanine.Ring-substituted mandelic acid, and the method for producing the same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-04-16 | — | — | EP | disclosed |