Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205771 | 1.00 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 | |
| SCHEMBL10710201 | 0.82 | NPC1 (0.39) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 | |
| SCHEMBL10991959 | 0.82 | NPC1 (0.39) | ALDH1A1NPC1RAB9APLA2G1BNFKB1 | |
| SCHEMBL31493860 | 0.81 | HSD17B10 (0.44) | ALDH1A1L3MBTL1HSD17B10KDM4EMAPT | |
| SCHEMBL9976117 | 0.81 | HSD17B10 (0.44) | ALDH1A1L3MBTL1HSD17B10KDM4EMAPT | |
| SCHEMBL3968879 | 0.81 | HSD17B10 (0.44) | ALDH1A1L3MBTL1HSD17B10KDM4EMAPT | |
| SCHEMBL3968881 | 0.81 | HSD17B10 (0.44) | ALDH1A1L3MBTL1HSD17B10KDM4EMAPT | |
| SCHEMBL4402096 | 0.80 | HSD17B10 (0.43) | ALDH1A1L3MBTL1HSD17B10KDM4EMAPT | |
| SCHEMBL4402093 | 0.80 | HSD17B10 (0.43) | ALDH1A1L3MBTL1HSD17B10KDM4EMAPT | |
| SCHEMBL4405615 | 0.80 | HSD17B10 (0.43) | ALDH1A1L3MBTL1HSD17B10KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027937-B1 | IMPROVED PROCESS FOR PRODUCING A MIXTURE CONTAINING CYCLOHEXANOL AND CYCLOHEXANONE FROM CYCLOHEXANE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-04-06 | — | — | EP | disclosed |
| US-4326084-A | TRANSITION METAL COMPLEX OF 1,3-BIS/PYRIDYLIMINO/ISOINDOLINE AS OXIDATION CATALYST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-04-20 | — | — | US | disclosed |
| EP-0048024-A1 | Improved process for producing 1,3-bis(2-pyridylimino)isoindolines and compositions containing transition metal complexes thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0027937-A1 | Improved process for producing a mixture containing cyclohexanol and cyclohexanone from cyclohexane | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-06 | — | — | EP | disclosed |