SCHEMBL11205862

SCHEMBL11205862

C(=C(/c1ccccc1)[SiH]1CCCCO1)\c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.35
ESR1 P03372 1/20 0.35
HPGD P15428 7/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
TRPA1 O75762 1/20 0.33
PRMT1 Q99873 1/20 0.33
ALDH1A1 P00352 4/20 0.31
MAPT P10636 4/20 0.31
LMNA P02545 3/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
UNG P13051 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP11B2 P19099 1/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11205869 1.00 AKR1C1 (0.35) AKR1C1ESR1HPGDMEN1KMT2A
SCHEMBL3274676 0.84
SCHEMBL485787 0.73
SCHEMBL27864330 0.72 MTNR1A (0.38) AKR1C1HPGDMEN1KMT2APRMT1
Styrene SCHEMBL18042449 0.70 ALDH1A1 (0.41) ALDH1A1
SCHEMBL21979730 0.67 TSHR (0.38) HPGDMEN1KMT2AALDH1A1KDM4E
SCHEMBL21638684 0.66 KDM1A (0.33) ALDH1A1MAPK1
SCHEMBL21638685 0.65 KDM1A (0.33) MEN1KMT2A
SCHEMBL6256499 0.64 TDP1 (0.31)
SCHEMBL8208405 0.64 MAOB (0.35) HPGDMEN1KMT2ATRPA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119790108-A Curable silicone composition, cured product thereof, laminate, and optical device or optical display 陶氏东丽株式会社 2025-04-08 CN disclosed
US-9550866-B2 Aryl group-containing siloxane compositions including alkaline earth metal DOW CORNING CORPORATION (US) 2017-01-24 US disclosed
EP-2970666-B1 ARYL GROUP-CONTAINING SILOXANE COMPOSITIONS INCLUDING ALKALINE EARTH METAL DOW CORNING (US) 2016-10-19 EP disclosed
US-20160027974-A1 Aryl Group-Containing Siloxane Compositions Including Alkaline Earth Metal DOW TORAY CO., LTD. (JP) 2016-01-28 US disclosed
EP-2970666-A2 ARYL GROUP-CONTAINING SILOXANE COMPOSITIONS INCLUDING ALKALINE EARTH METAL Dow Corning Corporation (US) 2016-01-20 EP disclosed
WO-2014149670-A2 ARYL GROUP-CONTAINING SILOXANE COMPOSITIONS INCLUDING ALKALINE EARTH METAL DOW CORNING CORPORATION (US) 2014-09-25 WO disclosed
EP-0012566-B1 ELECTRIC WINDINGS AND PRODUCTION THEREOF Hitachi, Ltd. (JP) 1983-06-22 EP disclosed
EP-0012566-A1 Electric windings and production thereof Hitachi, Ltd. (JP) 1980-06-25 EP disclosed
US-4198131-A Silicone resin optical devices DOW CORNING CORPORATION (US) 1980-04-15 US disclosed