SCHEMBL11205908

SCHEMBL11205908

CNC(=O)OCc1cccc(COC(=O)NC)c1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.47
TOP2A P11388 3/20 0.47
TOP2B Q02880 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
ALDH1A1 P00352 1/20 0.46
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
CYP3A4 P08684 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16015423 0.93 MAPT (0.45) MGLLTOP2ATOP2BNPC1RAB9A
SCHEMBL20109389 0.92 MGLL (0.42) MGLLTOP2ATOP2BNPC1RAB9A
SCHEMBL14543133 0.90 MEN1 (0.54) NPC1RAB9ALMNASMN1; SMN2MEN1
SCHEMBL6206459 0.88 TOP2A (0.52) MGLLTOP2ATOP2BNPC1RAB9A
SCHEMBL3151323 0.88 HCAR2 (0.56) CYP3A4
SCHEMBL24991645 0.88 IDO1 (0.50) MGLLTOP2ATOP2BNPC1RAB9A
SCHEMBL23849386 0.88 HCAR2 (0.56) ALDH1A1LMNACYP3A4
SCHEMBL15730048 0.87 NPC1 (0.64) NPC1RAB9AALDH1A1SMN1; SMN2MRGPRX4
Benzyl N-Methylcarbamate SCHEMBL645204 0.86 ALDH1A1 (0.62) MGLLTOP2ATOP2BNPC1RAB9A
SCHEMBL19830929 0.85 TSHR (0.55) TOP2ATOP2BLMNASMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0092738-A1 Process for the continuous thermal decomposition of carbamic-acid esters BAYER AG (DE) 1983-11-02 EP disclosed