Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206190 | 1.00 | NPSR1 (0.60) | NPSR1SMN1; SMN2KDM4ECTSLCTSB | |
| SCHEMBL2336933 | 0.90 | SMN1; SMN2 (0.58) | NPSR1SMN1; SMN2KDM4ECTSLCTSB | |
| SCHEMBL2336931 | 0.90 | SMN1; SMN2 (0.58) | NPSR1SMN1; SMN2KDM4ECTSLCTSB | |
| SCHEMBL837824 | 0.85 | SMN1; SMN2 (0.70) | NPSR1SMN1; SMN2KDM4ECA12CA1 | |
| SCHEMBL18838552 | 0.85 | SMN1; SMN2 (0.70) | NPSR1SMN1; SMN2KDM4ECA12CA1 | |
| SCHEMBL29446980 | 0.85 | SMN1; SMN2 (0.70) | NPSR1SMN1; SMN2KDM4ECA12CA1 | |
| SCHEMBL11198025 | 0.84 | ALDH1A1 (0.52) | NPSR1SMN1; SMN2KDM4ECTSLCTSB | |
| SCHEMBL11198020 | 0.84 | ALDH1A1 (0.52) | NPSR1SMN1; SMN2KDM4ECTSLCTSB | |
| SCHEMBL2473494 | 0.83 | CTSL (0.53) | NPSR1SMN1; SMN2KDM4ECTSLCTSB | |
| SCHEMBL3468963 | 0.83 | CTSL (0.53) | NPSR1SMN1; SMN2KDM4ECTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4411912-A | Insecticidal isovaleric acid esters | ZOECON CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |
| US-4243819-A | Substituted amino acids | ZOECON CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |