Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277725 | 0.95 | TSHR (0.34) | TDP1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL9823512 | 0.94 | TSHR (0.49) | TDP1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL5690811 | 0.94 | TSHR (0.46) | TDP1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL453283 | 0.92 | ALDH1A1 (0.50) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL3662482 | 0.90 | ALDH1A1 (0.43) | TDP1TSHRMAPK1TP53CYP3A4 | |
| Formaldehyde SCHEMBL9062631 | 0.89 | ALDH1A1 (0.48) | TSHRMAPK1TP53CYP3A4ALDH1A1 | |
| SCHEMBL5153493 | 0.86 | TSHR (0.40) | TSHRCYP3A4ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6536699 | 0.83 | TSHR (0.31) | TSHRLMNA | |
| SCHEMBL1982818 | 0.82 | ALDH1A1 (0.37) | TDP1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL3911174 | 0.81 | CRHBP (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414230-A | BLEND OF A POLYESTER-CARBONATE COPOLYMER AND A POLYESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-11-08 | — | — | US | claimed |
| US-4414230-A | BLEND OF A POLYESTER-CARBONATE COPOLYMER AND A POLYESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-11-08 | — | — | US | disclosed |