Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 8/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 7/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 7/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 7/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | SCN1A | P35498 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206664 | 1.00 | CACNA1C (0.53) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL10923491 | 0.96 | CACNA1C (0.52) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL10922943 | 0.94 | CACNA1D (0.50) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL6427366 | 0.92 | CACNA1D (0.57) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL10528018 | 0.90 | CACNA1D (0.55) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL10926071 | 0.89 | CACNA1C (0.45) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL6425245 | 0.89 | CACNA1D (0.61) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL6427770 | 0.88 | ADORA3 (0.67) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL11117647 | 0.87 | CACNA1D (0.56) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL11116035 | 0.86 | ADORA3 (0.55) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088276-A1 | Compounds, process for their preparation and their use as pharmaceutical preparations | BAYER AG (DE) | 1983-09-14 | — | — | EP | disclosed |