Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241355 | 0.94 | MEN1 (0.51) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL10814271 | 0.93 | MEN1 (0.52) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL2575493 | 0.90 | MEN1 (0.48) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL10816275 | 0.87 | MEN1 (0.47) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL11198219 | 0.86 | PDE3A (0.43) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL11204296 | 0.86 | PDE3A (0.46) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL11199339 | 0.85 | PDE3A (0.42) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL11207741 | 0.84 | PDE3A (0.41) | MEN1KMT2AALDH1A1LMNACYP3A4 | |
| SCHEMBL8905608 | 0.83 | HPRT1 (0.39) | TYMP | |
| SCHEMBL5930471 | 0.82 | TK1 (0.47) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085424-A2 | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1983-08-10 | — | — | EP | disclosed |