SCHEMBL8905608

SCHEMBL8905608

CCOP(=O)(COC(COC(c1ccccc1)(c1ccccc1)c1ccc(OC)cc1)Cn1cnc2c(=O)[nH]c(NC(c3ccccc3)(c3ccccc3)c3ccc(OC)cc3)nc21)OCC

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 11/20 0.39
TYMP P19971 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11206457 0.83 MEN1 (0.45) TYMP
SCHEMBL14037059 0.79 P2RY1 (0.40)
SCHEMBL10814271 0.77 MEN1 (0.52)
SCHEMBL11199339 0.76 PDE3A (0.42)
SCHEMBL3241355 0.76 MEN1 (0.51) HPRT1
SCHEMBL10816275 0.76 MEN1 (0.47) HPRT1
SCHEMBL11204296 0.75 PDE3A (0.46)
SCHEMBL11198219 0.75 PDE3A (0.43) HPRT1
SCHEMBL11207741 0.75 PDE3A (0.41)
SCHEMBL5930471 0.74 TK1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5650510-A VIRICIDES OR ANTITUMOR AGENTS INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1997-07-22 US disclosed
EP-0269947-A1 Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1988-06-08 EP disclosed