Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 7/20 | 0.54 |
| ▸ | PGR | P06401 | 6/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | SHBG | P04278 | 1/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203342 | 0.94 | AR (0.50) | ARLMNAPGRCYP3A4SMN1; SMN2 | |
| SCHEMBL11205510 | 0.90 | LMNA (0.55) | ARLMNAPGRCYP3A4SMN1; SMN2 | |
| SCHEMBL11239936 | 0.89 | AR (0.48) | ARLMNAPGRCYP3A4SMN1; SMN2 | |
| SCHEMBL11237524 | 0.89 | AR (0.57) | ARLMNAPGRCYP3A4SMN1; SMN2 | |
| SCHEMBL13941337 | 0.88 | LMNA (0.67) | ARLMNAPGRCYP3A4SMN1; SMN2 | |
| SCHEMBL9622429 | 0.88 | LMNA (0.67) | ARLMNAPGRCYP3A4SMN1; SMN2 | |
| SCHEMBL853001 | 0.88 | LMNA (0.67) | ARLMNAPGRCYP3A4SMN1; SMN2 | |
| SCHEMBL11205039 | 0.88 | NR3C1 (0.60) | ARLMNAPGRCYP3A4SMN1; SMN2 | |
| SCHEMBL835740 | 0.85 | AR (0.68) | ARLMNAPGRCYP3A4SMN1; SMN2 | |
| SCHEMBL9622215 | 0.85 | AR (0.68) | ARLMNAPGRCYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034115-B1 | PROCESS FOR THE PREPARATION OF 6-METHYLENE STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-06-08 | — | — | EP | disclosed |
| US-4322349-A | Process for preparing 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |
| EP-0034115-A2 | Process for the preparation of 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-08-19 | — | — | EP | disclosed |