Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.69 |
| ▸ | PGR | P06401 | 6/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.65 |
| ▸ | AR | P10275 | 3/20 | 0.65 |
| ▸ | F2 | P00734 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | IL6 | P05231 | 1/20 | 0.49 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | GLUL | P15104 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207168 | 1.00 | NR3C1 (0.69) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL11207101 | 0.92 | NR3C1 (0.82) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL11207103 | 0.92 | NR3C1 (0.82) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL11326470 | 0.91 | NR3C1 (0.81) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL11329966 | 0.91 | NR3C1 (0.81) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL11329949 | 0.91 | NR3C1 (0.81) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL3688125 | 0.88 | PGR (0.83) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL9275838 | 0.88 | PGR (0.83) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL11329958 | 0.86 | NR3C1 (0.82) | NR3C1PGRCYP3A4ARF2 | |
| SCHEMBL11201742 | 0.86 | NR3C1 (0.82) | NR3C1PGRCYP3A4ARF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010056-B1 | CORTICOID SULFOPROPIONIC ACID ESTERS AND THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-08-24 | — | — | EP | claimed |
| US-4296109-A | ANTISHOCK, ANTIINFLAMMATORY | SCHERING, AKTIENGESELLSCHAFT (DE) | 1981-10-20 | — | — | US | claimed |
| US-4296109-A | ANTISHOCK, ANTIINFLAMMATORY | SCHERING, AKTIENGESELLSCHAFT (DE) | 1981-10-20 | — | — | US | disclosed |