SCHEMBL11207176

SCHEMBL11207176

CCCc1cc(S)c(S)cc1C

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.35
HMGCR P04035 1/20 0.32
TAAR1 Q96RJ0 1/20 0.30
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 2/20 0.30
HPGD P15428 2/20 0.30
HSD17B10 Q99714 2/20 0.30
POLB P06746 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30369685 0.77 NPSR1 (0.44) NPSR1HMGCRTAAR1KDM4EALDH1A1
SCHEMBL597339 0.77 NPSR1 (0.44) NPSR1HMGCRTAAR1KDM4EALDH1A1
SCHEMBL27540125 0.73 PRKCI (0.32) HMGCRTAAR1
SCHEMBL10332935 0.73 TAAR1 (0.41) HMGCRTAAR1TSHR
SCHEMBL13375177 0.71 ALDH1A1 (0.48) NPSR1HMGCRTAAR1KDM4EALDH1A1
SCHEMBL5678026 0.71 HMGCR (0.45) NPSR1HMGCRKDM4EALDH1A1HPGD
SCHEMBL29314105 0.71 HMGCR (0.36) NPSR1HMGCRTAAR1KDM4EALDH1A1
SCHEMBL23387409 0.70 HMGCR (0.53) NPSR1HMGCRKDM4EALDH1A1HPGD
SCHEMBL7740682 0.70 HMGCR (0.31) HMGCR
SCHEMBL21386521 0.70 NPSR1 (0.39) NPSR1HMGCRTAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108431149-B Anti-biofouling coatings based on epoxy resins and amine functional polysiloxanes 陶氏环球技术有限责任公司 2020-11-20 CN disclosed
US-20180355189-A1 ANTI-BIOFOULING COATING BASED ON EPOXY RESIN AND AMINE-FUNCTIONAL POLYSILOXANE ROHM AND HAAS COMPANY 2018-12-13 US disclosed
EP-0014745-B1 CURING AGENT FOR POLYEPOXIDES, CURABLE EPOXY RESIN COMPOSITIONS, HARDENED PRODUCTS THEREFROM AND PROCESS FOR CURING A POLYEPOXIDE DIAMOND SHAMROCK CORPORATION (US) 1983-05-25 EP disclosed
EP-0075827-A2 Polyepoxide curing by polymercaptans plus catalytic co-curing agents DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1983-04-06 EP disclosed
EP-0014745-A1 Curing agent for polyepoxides, curable epoxy resin compositions, hardened products therefrom and process for curing a polyepoxide DIAMOND SHAMROCK CORPORATION (US) 1980-09-03 EP disclosed
US-4177173-A INFUSIBLE FILMS, CASTINGS OR ADHESIVES DIAMOND SHAMROCK CORPORATION (US) 1979-12-04 US disclosed