Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679856 | 0.91 | HMGCR (0.50) | HMGCRNPSR1ALOX5PTPN1PTPN11 | |
| SCHEMBL18924281 | 0.91 | HMGCR (0.53) | HMGCRNPSR1ALOX5PTPN1PTPN11 | |
| SCHEMBL5678026 | 0.88 | HMGCR (0.45) | HMGCRNPSR1ALOX5PTPN1PTPN11 | |
| SCHEMBL4010705 | 0.87 | TYR (0.55) | HMGCRNPSR1ALOX5TYRMAPT | |
| SCHEMBL14139877 | 0.86 | NPSR1 (0.46) | HMGCRNPSR1ALOX5PTPN1PTPN11 | |
| SCHEMBL13842565 | 0.86 | HMGCR (0.53) | HMGCRNPSR1ALOX5PTPN1PTPN11 | |
| SCHEMBL11024762 | 0.85 | HMGCR (0.61) | HMGCRALOX5PTPN1PTPN11TYR | |
| SCHEMBL28233540 | 0.85 | TYR (0.53) | HMGCRNPSR1ALOX5TYRMAPT | |
| SCHEMBL2775231 | 0.84 | ALOX5 (0.58) | ALOX5TYRMAPTHTTMEN1 | |
| SCHEMBL1760537 | 0.83 | HMGCR (0.64) | HMGCRALOX5PTPN1PTPN11TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825145-A1 | TIRE RUBBER COMPOSITION AND TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2021-05-26 | — | — | EP | disclosed |