Formaldehyde

Formaldehyde

SCHEMBL11207342

C=O.NO.Nc1nc(N)nc(N)n1

nearest known ligand 0.48

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
CYP1A2 P05177 1/20 0.43
CASP1 P29466 1/20 0.38
POLB P06746 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSP90AA1 P07900 1/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 1/20 0.31
PDPK1 O15530 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL20816 0.92 LMNA (0.45) LMNACYP1A2CASP1POLBADORA3
Formaldehyde SCHEMBL3301090 0.92 LMNA (0.45) LMNACYP1A2CASP1POLBADORA3
Formaldehyde SCHEMBL7797548 0.92 LMNA (0.45) LMNACYP1A2CASP1POLBADORA3
Formaldehyde SCHEMBL6550879 0.92 LMNA (0.45) LMNACYP1A2CASP1POLBADORA3
Formaldehyde SCHEMBL11786670 0.92 LMNA (0.45) LMNACYP1A2CASP1POLBADORA3
Formaldehyde SCHEMBL9861640 0.92 LMNA (0.45) LMNACYP1A2CASP1POLBADORA3
Urea SCHEMBL11325879 0.90 CYP1A2 (0.44) LMNACYP1A2CASP1ADORA2AADORA1
Formaldehyde SCHEMBL2823810 0.89 LMNA (0.52) LMNACYP1A2CASP1POLBADORA3
Formaldehyde SCHEMBL11376350 0.88 LMNA (0.43) LMNACYP1A2CASP1POLBADORA3
Formaldehyde SCHEMBL21633883 0.88 LMNA (0.43) LMNACYP1A2CASP1POLBADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0007705-B1 MODIFIED AMINOPLAST CONDENSATION PRODUCTS AND PROCESS FOR THEIR PREPARATION BRITISH INDUSTRIAL PLASTICS LIMITED (GB) 1983-02-16 EP disclosed