Urea — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	CYP1A2	P05177	2/20	0.44

▸	LMNA	P02545	2/20	0.42

▸	ALDH1A1	P00352	2/20	0.38

▸	OR51E2	Q9H255	1/20	0.38

▸	TDP1	Q9NUW8	1/20	0.38

▸	PDPK1	O15530	1/20	0.37

▸	CASP1	P29466	1/20	0.33

▸	HSP90AB1	P08238	1/20	0.32

▸	KDM4E	B2RXH2	1/20	0.31

▸	HPGD	P15428	1/20	0.31

▸	ADORA2A	P29274	1/20	0.31

▸	ADORA1	P30542	1/20	0.31

▸	SMN1; SMN2	Q16637	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Urea SCHEMBL6052731	0.97	CYP1A2 (0.46)	CYP1A2LMNAALDH1A1OR51E2TDP1
Urea SCHEMBL574673	0.97	CYP1A2 (0.46)	CYP1A2LMNAALDH1A1OR51E2TDP1
Urea SCHEMBL11663512	0.90	CYP1A2 (0.46)	CYP1A2LMNAALDH1A1OR51E2TDP1
Formaldehyde SCHEMBL11207342	0.90	LMNA (0.48)	CYP1A2LMNAPDPK1CASP1ADORA2A
Urea SCHEMBL51851	0.90	CYP1A2 (0.50)	CYP1A2LMNAALDH1A1OR51E2TDP1
Urea SCHEMBL10914180	0.90	CYP1A2 (0.50)	CYP1A2LMNAALDH1A1OR51E2TDP1
Urea SCHEMBL15483993	0.90	CYP1A2 (0.50)	CYP1A2LMNAALDH1A1OR51E2TDP1
Urea SCHEMBL28050095	0.87	CYP1A2 (0.48)	CYP1A2LMNAALDH1A1OR51E2TDP1
Urea SCHEMBL28466157	0.87	CYP1A2 (0.48)	CYP1A2LMNAALDH1A1OR51E2TDP1
Urea SCHEMBL4899185	0.84	CYP1A2 (0.46)	CYP1A2LMNAALDH1A1OR51E2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4250069-A	WITH UREA AND ALIPHATIC HYDROXYMONOAMINE; WATER SOLUBLE, CATIONIC	BRITISH INDUSTRIAL PLASTICS, LIMITED (GB)	1981-02-10	—	—	US	disclosed