Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210334 | 0.95 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL6777555 | 0.84 | IDO1 (0.44) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL11353500 | 0.83 | TDP1 (0.54) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL8324377 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1MAPK1LMNA | |
| SCHEMBL11347968 | 0.79 | PPARG (0.42) | ALDH1A1KMT2AMEN1LMNARAB9A | |
| SCHEMBL9052172 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL25933057 | 0.78 | TDP1 (0.59) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL5242448 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL8643591 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL28293889 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019587-B1 | CARBOXYLIC ACID HYDRAZIDES, PROCESS FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-07-20 | — | — | EP | disclosed |
| US-4296128-A | ANTITHROMBOSIS AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-10-20 | — | — | US | disclosed |
| EP-0019587-A1 | Carboxylic acid hydrazides, process for their preparation, their use and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-11-26 | — | — | EP | disclosed |