Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216125 | 0.92 | LMNA (0.48) | CYP1A2CYP2A6TAAR1TDP1NPC1 | |
| SCHEMBL840528 | 0.86 | CYP1A2 (0.50) | CYP1A2CYP2A6TAAR1IDO1HRH3 | |
| SCHEMBL446130 | 0.84 | CYP1A2 (0.48) | CYP1A2CYP2A6TAAR1IDO1HRH3 | |
| SCHEMBL14078071 | 0.80 | CYP1A2 (0.45) | CYP1A2CYP2A6TAAR1IDO1HRH3 | |
| SCHEMBL24602755 | 0.78 | CYP1A2 (0.52) | CYP1A2CYP2A6TAAR1IDO1HRH3 | |
| SCHEMBL8859946 | 0.77 | KMT2A (0.43) | CYP1A2CYP2A6TAAR1ACHENPC1 | |
| SCHEMBL143961 | 0.76 | CYP1A2 (0.68) | CYP1A2CYP2A6TAAR1IDO1HRH3 | |
| SCHEMBL11288839 | 0.76 | CYP1A2 (0.68) | CYP1A2CYP2A6TAAR1IDO1HRH3 | |
| SCHEMBL11120539 | 0.76 | KCNH2 (0.47) | CYP1A2KCNH2NPC1RAB9ACNR1 | |
| SCHEMBL1030793 | 0.75 | TDP1 (0.52) | CYP1A2CYP2A6TAAR1IDO1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269993-A | Diaralkyldichlorosilanes | CHISSO CORPORATION (JP) | 1981-05-26 | — | — | US | claimed |
| EP-0028665-A1 | Process for the production of diaralkyldichlorosilanes and their use in manufacture of polysiloxane | Chisso Corporation (JP) | 1981-05-20 | — | — | EP | claimed |
| EP-0028665-B1 | PROCESS FOR THE PRODUCTION OF DIARALKYLDICHLOROSILANES AND THEIR USE IN MANUFACTURE OF POLYSILOXANE | Chisso Corporation (JP) | 1983-05-18 | — | — | EP | disclosed |
| US-4269993-A | Diaralkyldichlorosilanes | CHISSO CORPORATION (JP) | 1981-05-26 | — | — | US | disclosed |
| EP-0028665-A1 | Process for the production of diaralkyldichlorosilanes and their use in manufacture of polysiloxane | Chisso Corporation (JP) | 1981-05-20 | — | — | EP | disclosed |