Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848455 | 0.87 | CA2 (0.38) | CYP1A2CYP2A6TAAR1IDO1TDP1 | |
| SCHEMBL11207430 | 0.86 | CYP1A2 (0.50) | CYP1A2CYP2A6TAAR1IDO1HRH3 | |
| Toluene SCHEMBL18394201 | 0.85 | LMNA (0.46) | CYP1A2TAAR1IDO1ALOX15ACHE | |
| SCHEMBL446130 | 0.84 | CYP1A2 (0.48) | CYP1A2CYP2A6TAAR1IDO1HRH3 | |
| SCHEMBL14078071 | 0.80 | CYP1A2 (0.45) | CYP1A2CYP2A6TAAR1IDO1HRH3 | |
| SCHEMBL11216125 | 0.79 | LMNA (0.48) | CYP1A2CYP2A6TAAR1TDP1NPC1 | |
| SCHEMBL24602755 | 0.78 | CYP1A2 (0.52) | CYP1A2CYP2A6TAAR1IDO1HRH3 | |
| SCHEMBL5490774 | 0.78 | TAAR1 (0.52) | CYP1A2CYP2A6TAAR1IDO1IGF1R | |
| SCHEMBL926567 | 0.78 | CA2 (0.37) | TAAR1 | |
| SCHEMBL8859946 | 0.77 | KMT2A (0.43) | CYP1A2CYP2A6TAAR1ACHENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310446-B1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-23 | — | — | EP | disclosed |
| CN-102432924-B | Rubber composition, process of preparing same and articles made therefrom | MOMENTIVE PERFORMANCE MAT INC | 2014-04-09 | — | — | CN | disclosed |
| CN-102177197-B | Activated halo-containing aralkylsilane | MOMENTIVE PERFORMANCE MAT INC | 2013-11-06 | — | — | CN | disclosed |
| CN-101641226-B | Rubber composition, method of making the same, and articles made therefrom | MOMENTIVE PERFORMANCE MAT INC | 2013-02-13 | — | — | CN | disclosed |
| CN-102432924-A | Rubber composition, method of making the same, and articles made therefrom | MOMENTIVE PERFORMANCE MAT INC | 2012-05-02 | — | — | CN | disclosed |
| US-8143336-B2 | Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-03-27 | — | — | US | disclosed |
| CN-102177197-A | Activated halo-containing aralkylsilane | MOMENTIVE PERFORMANCE MAT INC | 2011-09-07 | — | — | CN | disclosed |
| EP-2310446-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | Momentive Performance Materials Inc. (US) | 2011-04-20 | — | — | EP | disclosed |
| EP-2121349-B1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2010-11-17 | — | — | EP | disclosed |
| US-20100036018-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-02-11 | — | — | US | disclosed |
| EP-1244676-B1 | SULFUR-CONTAINING SILANE AS COUPLING AGENTS | GEN ELECTRIC (US) | 2004-10-13 | — | — | EP | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |
| US-20040082803-A1 | Trichlorosilyl groups containing organochlorosilanes and their preparation methods by the double-silylation of olefins with trichlorosilane | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2004-04-29 | — | — | US | disclosed |
| US-6518335-B2 | Made by chlorine-free process by reacting alkoxysilane acetals such as (3,3-dimethoxypropyl)trimethoxysilane with sulfurating agents such as sulfur, hydrogen sulfide, or thiols; use in silica-filled rubbers | CROMPTON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| CN-1394208-A | Sulfur-containing silane coupling agents | CROMPTON CORP (US) | 2003-01-29 | — | — | CN | disclosed |
| EP-1244676-A1 | SULFUR-CONTAINING SILANE AS COUPLING AGENTS | Crompton Corporation (US) | 2002-10-02 | — | — | EP | disclosed |
| US-20020002220-A1 | SULFUR-CONTAINING SILANE COUPLING AGENTS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2002-01-03 | — | — | US | disclosed |
| WO-2001049695-A1 | SULFUR-CONTAINING SILANE AS COUPLING AGENTS | CROMPTON CORPORATION (US) | 2001-07-12 | — | — | WO | disclosed |
| US-4099981-A | MINERAL FILLER | UNION CARBIDE CORPORATION (US) | 1978-07-11 | — | — | US | disclosed |
| US-4044037-A | COUPLING AGENTS | UNION CARBIDE CORPORATION (US) | 1977-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082803-A1 | Trichlorosilyl groups containing organochlorosilanes and their preparation methods by the double-silylation of olefins with trichlorosilane | CBR1, OXSR1, HCCS | CYP1A2 790/4885CYP2A6 706/4885TAAR1 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.