SCHEMBL1120745

SCHEMBL1120745

CC1=Cc2c(C(C)C)cc(C(C)C)cc2C1[Hf](C1C(C)=Cc2c(C(C)C)cc(C(C)C)cc21)[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
FABP3 P05413 1/20 0.30
FABP4 P15090 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2233916 0.99 GABRA1 (0.30) GABRA1GABRB2
SCHEMBL28411939 0.83 GABRA1 (0.33) GABRA1GABRB2FABP3FABP4
SCHEMBL12475394 0.82 GABRA1 (0.33) GABRA1GABRB2FABP3FABP4
SCHEMBL12475396 0.82 GABRA1 (0.33) GABRA1GABRB2FABP3FABP4
SCHEMBL16415244 0.81 GABRA1 (0.34) GABRA1GABRB2FABP3FABP4
SCHEMBL5188314 0.81 GABRA1 (0.32) GABRA1GABRB2FABP3FABP4
Hydrochloric Acid SCHEMBL7211438 0.78 FABP4 (0.31) GABRA1GABRB2FABP4
Hydrochloric Acid SCHEMBL8823402 0.73 GABRA1 (0.31) GABRA1GABRB2FABP3FABP4
SCHEMBL2232311 0.73 GABRA1 (0.31) GABRA1GABRB2FABP3FABP4
SCHEMBL8506274 0.73 GABRA1 (0.35) GABRA1GABRB2FABP3FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799726-B1 TRIALKYLALUMINUM TREATED SUPPORTS EXXONMOBIL CHEM PATENTS INC (US) 2011-07-13 EP claimed
EP-3022234-B1 SUBSTITUTED METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-12-26 EP disclosed
US-9938364-B2 Substituted metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-04-10 US disclosed
US-20170015767-A1 Substituted Metallocene Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2017-01-19 US disclosed
US-9458254-B2 Substituted metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-10-04 US disclosed
EP-3022234-A1 SUBSTITUTED METALLOCENE CATALYSTS ExxonMobil Chemical Patents Inc. (US) 2016-05-25 EP disclosed
US-20150025209-A1 Substituted Metallocene Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2015-01-22 US disclosed
WO-2015009479-A1 SUBSTITUTED METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-01-22 WO disclosed
EP-2102282-B1 MULTIMODAL POLYETHYLENE COMPOSITION, MIXED CATALYST AND PROCESS FOR PREPARING THE COMPOSITION BASELL POLYOLEFINE GMBH (DE) 2011-02-09 EP disclosed