Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.49 |
| ▸ | ELANE | P08246 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10418402 | 0.80 | AKR1C3 (0.55) | AKR1C3ELANEMAPTGAAALDH1A1 | |
| SCHEMBL10361994 | 0.79 | GAA (0.44) | ELANEMAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL11207345 | 0.78 | AKR1C3 (0.49) | AKR1C3MAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL11146578 | 0.78 | AKR1C3 (0.52) | AKR1C3ELANEMAPTGAAALDH1A1 | |
| SCHEMBL11149732 | 0.75 | TSHR (0.54) | AKR1C3ALDH1A1HSD17B10CDC25BTSHR | |
| SCHEMBL11210728 | 0.74 | AKR1C3 (0.47) | AKR1C3MAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL29447165 | 0.73 | AKR1C3 (0.85) | AKR1C3MAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL700595 | 0.73 | AKR1C3 (0.85) | AKR1C3MAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL9502647 | 0.73 | AKR1C3 (0.59) | AKR1C3ELANEMAPTGAAALDH1A1 | |
| SCHEMBL14330484 | 0.72 | ELANE (0.68) | AKR1C3ELANEMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035291-B1 | PROCESS FOR CARRYING OUT RADICAL REACTIONS AND SHAPED ARTICLES OF THE REACTION PRODUCT | AKZO N.V. (NL) | 1983-05-11 | — | — | EP | disclosed |
| US-4347342-A | Process for initiating radical reactions employing hydroximic acid derivatives | AKZONA INCORPORATED (US) | 1982-08-31 | — | — | US | disclosed |