Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149732 | 0.87 | TSHR (0.54) | AKR1C3TSHRALDH1A1L3MBTL1POLB | |
| SCHEMBL195278 | 0.80 | TSHR (0.75) | AKR1C3TSHRALDH1A1NPC1MEN1 | |
| SCHEMBL29619268 | 0.80 | TSHR (0.75) | AKR1C3TSHRALDH1A1NPC1MEN1 | |
| SCHEMBL6920338 | 0.79 | MEN1 (0.44) | TSHRALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL28224263 | 0.78 | ALDH1A1 (0.58) | AKR1C3TSHRALDH1A1NPC1MAPT | |
| SCHEMBL11207455 | 0.78 | AKR1C3 (0.49) | AKR1C3TSHRALDH1A1MAPTKMT2A | |
| SCHEMBL11146578 | 0.78 | AKR1C3 (0.52) | AKR1C3TSHRALDH1A1MAPTKMT2A | |
| SCHEMBL11143475 | 0.77 | TSHR (0.48) | TSHRALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL7753073 | 0.77 | TSHR (0.42) | TSHRALDH1A1NPC1MAPTMEN1 | |
| SCHEMBL11210728 | 0.74 | AKR1C3 (0.47) | AKR1C3ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035291-B1 | PROCESS FOR CARRYING OUT RADICAL REACTIONS AND SHAPED ARTICLES OF THE REACTION PRODUCT | AKZO N.V. (NL) | 1983-05-11 | — | — | EP | disclosed |
| US-4347342-A | Process for initiating radical reactions employing hydroximic acid derivatives | AKZONA INCORPORATED (US) | 1982-08-31 | — | — | US | disclosed |