Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207345 | 0.87 | AKR1C3 (0.49) | TSHRL3MBTL1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL11204533 | 0.85 | TSHR (0.57) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL818749 | 0.84 | TSHR (0.78) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL10694796 | 0.83 | TSHR (0.47) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL18473273 | 0.79 | TSHR (0.79) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL10482944 | 0.78 | ALDH1A1 (0.79) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL820186 | 0.78 | ALDH1A1 (0.79) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL1790206 | 0.78 | ALDH1A1 (0.79) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL818473 | 0.78 | ALDH1A1 (0.79) | TSHRL3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL6820105 | 0.77 | LMNA (0.50) | TSHRTDP1ALDH1A1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4374938-A | HYDROXIMIC ACID DERIVATIVE AS FREE RADICAL INITIATOR | AKZONA INCORPORATED (US) | 1983-02-22 | — | — | US | disclosed |
| US-4347342-A | Process for initiating radical reactions employing hydroximic acid derivatives | AKZONA INCORPORATED (US) | 1982-08-31 | — | — | US | disclosed |