Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 7/20 | 0.71 |
| ▸ | SERPINA6 | P08185 | 6/20 | 0.71 |
| ▸ | LMNA | P02545 | 6/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.71 |
| ▸ | BLM | P54132 | 4/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.71 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.71 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | PGR | P06401 | 2/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.63 |
| ▸ | HTR2B | P41595 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29694165 | 0.88 | MEN1 (0.72) | SHBGSERPINA6LMNASMN1; SMN2BLM | |
| Hydroxyprogesterone SCHEMBL18261234 | 0.83 | LMNA (1.00) | SHBGSERPINA6LMNASMN1; SMN2BLM | |
| Hydroxyprogesterone SCHEMBL265609 | 0.83 | LMNA (1.00) | SHBGSERPINA6LMNASMN1; SMN2BLM | |
| Hydroxyprogesterone SCHEMBL13558389 | 0.83 | LMNA (1.00) | SHBGSERPINA6LMNASMN1; SMN2BLM | |
| Hydroxyprogesterone SCHEMBL24287585 | 0.83 | LMNA (1.00) | SHBGSERPINA6LMNASMN1; SMN2BLM | |
| Hydroxyprogesterone SCHEMBL23456341 | 0.83 | LMNA (1.00) | SHBGSERPINA6LMNASMN1; SMN2BLM | |
| Hydroxyprogesterone SCHEMBL14523053 | 0.83 | LMNA (1.00) | SHBGSERPINA6LMNASMN1; SMN2BLM | |
| Hydroxyprogesterone SCHEMBL3931615 | 0.83 | LMNA (1.00) | SHBGSERPINA6LMNASMN1; SMN2BLM | |
| Hydroxyprogesterone SCHEMBL14546356 | 0.83 | LMNA (1.00) | SHBGSERPINA6LMNASMN1; SMN2BLM | |
| Hydroxyprogesterone SCHEMBL30657985 | 0.83 | LMNA (1.00) | SHBGSERPINA6LMNASMN1; SMN2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034115-B1 | PROCESS FOR THE PREPARATION OF 6-METHYLENE STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-06-08 | — | — | EP | disclosed |
| US-4322349-A | Process for preparing 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |
| EP-0034115-A2 | Process for the preparation of 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-08-19 | — | — | EP | disclosed |