Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2639604 | 0.83 | NPC1 (0.54) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL11339350 | 0.81 | PTGS1 (0.44) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL11339346 | 0.81 | PTGS1 (0.44) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL11201833 | 0.81 | RAB9A (0.45) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL11349351 | 0.80 | MAPT (0.49) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL11182616 | 0.78 | MEN1 (0.56) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL11872871 | 0.77 | MEN1 (0.55) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL9298091 | 0.76 | KEAP1 (0.52) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL9298095 | 0.76 | KEAP1 (0.52) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL4448947 | 0.76 | HPGD (0.54) | MEN1KMT2ARAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006713-B1 | NOVEL ALPHA-AMINO-PHENYLACETIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS HERBICIDAL, ALGICIDAL AND PLANT GROWTH REGULATING AGENTS, AND HERBICIDAL, ALGICIDAL AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-07-13 | — | — | EP | disclosed |
| US-4246429-A | HERBICIDES, ALGICIDES, PLANT GROWTH REGULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1981-01-20 | — | — | US | disclosed |
| EP-0006713-A1 | Novel alpha-amino-phenylacetic acid derivatives, processes for their preparation, their use as herbicidal, algicidal and plant growth regulating agents, and herbicidal, algicidal and plant growth regulating compositions containing them | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-01-09 | — | — | EP | disclosed |