Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195261 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EPOLBHPGDMEN1 | |
| SCHEMBL27589707 | 0.76 | KDM4E (0.50) | ALDH1A1KDM4EPOLBHPGDMEN1 | |
| SCHEMBL9198796 | 0.73 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBHPGDMEN1 | |
| SCHEMBL11243813 | 0.72 | CNR2 (0.61) | CNR1CNR2 | |
| SCHEMBL27443583 | 0.71 | ALDH1A1 (0.63) | ALDH1A1KDM4EPOLBHPGDMEN1 | |
| SCHEMBL729021 | 0.71 | ALDH1A1 (0.56) | ALDH1A1KDM4EPOLBHPGDMEN1 | |
| SCHEMBL9416196 | 0.70 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBHPGDMEN1 | |
| SCHEMBL11761679 | 0.70 | CASP1 (0.48) | ALDH1A1KDM4EPOLBHPGDMEN1 | |
| SCHEMBL11260630 | 0.70 | CNR2 (0.64) | CNR1CNR2 | |
| SCHEMBL11492278 | 0.70 | PTGDR2 (0.45) | ALDH1A1KDM4EPOLBHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4381266-A | (N-Substituted benzoyl)halobenzoic acid anhydrides | CIBA-GEIGY CORPORATION (US) | 1983-04-26 | — | — | US | disclosed |
| US-4277400-A | 2(Indol-3'-oyl) 3,4,5,6-tetrahalo benzoic acid anhydrides | CIBA-GEIGY CORPORATION (US) | 1981-07-07 | — | — | US | disclosed |
| US-4119776-A | Vinyl phthalide color formers | NCR CORPORATION (US) | 1978-10-10 | — | — | US | disclosed |