Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.77 |
| ▸ | ACHE | P22303 | 16/20 | 0.60 |
| ▸ | BCHE | P06276 | 10/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995056 | 0.87 | PRMT6 (1.00) | PRMT6ACHEBCHE | |
| Hydrochloric Acid SCHEMBL8004700 | 0.85 | PRMT6 (0.97) | PRMT6ACHEBCHE | |
| Hydrochloric Acid SCHEMBL8601128 | 0.85 | PRMT6 (0.97) | PRMT6ACHEBCHE | |
| SCHEMBL10857632 | 0.84 | PRMT6 (0.68) | PRMT6ACHEBCHE | |
| SCHEMBL10741993 | 0.83 | PRMT6 (0.74) | PRMT6ACHEBCHE | |
| SCHEMBL11366646 | 0.81 | PRMT6 (0.71) | PRMT6ACHEBCHE | |
| SCHEMBL11469914 | 0.79 | PRMT6 (0.68) | PRMT6ACHEBCHE | |
| SCHEMBL11480563 | 0.78 | PRMT6 (0.67) | PRMT6ACHEBCHE | |
| SCHEMBL10960228 | 0.78 | PRMT6 (0.67) | PRMT6ACHEBCHE | |
| SCHEMBL11214116 | 0.78 | PRMT6 (0.62) | PRMT6ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002930-B1 | AMINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1983-12-14 | — | — | EP | disclosed |
| US-4304780-A | Aminoalkylthiophene derivatives as histamine H2 -antagonists | GLAXO GROUP LIMITED (GB) | 1981-12-08 | — | — | US | disclosed |
| US-4279911-A | ANTIHISTAMINES | GLAXO GROUP LIMITED (GB) | 1981-07-21 | — | — | US | disclosed |
| US-4233302-A | ANTIHISTAMINES, ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1980-11-11 | — | — | US | disclosed |
| EP-0002930-A1 | Amine derivatives, their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1979-07-11 | — | — | EP | disclosed |