SCHEMBL11366646

SCHEMBL11366646

CCN(CC)Cc1ccc(CSCCN)o1

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.71
ACHE P22303 16/20 0.56
BCHE P06276 10/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10741993 0.86 PRMT6 (0.74) PRMT6ACHEBCHE
SCHEMBL10857632 0.84 PRMT6 (0.68) PRMT6ACHEBCHE
SCHEMBL7995056 0.83 PRMT6 (1.00) PRMT6ACHEBCHE
Hydrochloric Acid SCHEMBL8601128 0.82 PRMT6 (0.97) PRMT6ACHEBCHE
Hydrochloric Acid SCHEMBL8004700 0.82 PRMT6 (0.97) PRMT6ACHEBCHE
SCHEMBL11207862 0.81 PRMT6 (0.77) PRMT6ACHEBCHE
SCHEMBL11461626 0.80 PRMT6 (0.61) PRMT6ACHEBCHE
SCHEMBL11361537 0.77 PRMT6 (0.66) PRMT6ACHEBCHE
SCHEMBL11479765 0.76 PRMT6 (0.42) PRMT6ACHEBCHE
SCHEMBL11469914 0.76 PRMT6 (0.68) PRMT6ACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4279819-A GASTROINTESTINAL DISORDERS ALLEN & HANBURYS LTD. (GB) 1981-07-21 US claimed
US-4279819-A GASTROINTESTINAL DISORDERS ALLEN & HANBURYS LTD. (GB) 1981-07-21 US disclosed
US-4255440-A ANTIALLERGENS, ANTIULCER AGENTS ALLEN & HANBURYS LIMITED (GB) 1981-03-10 US disclosed
US-4203909-A ANTIULCER BRISTOL-MYERS COMPANY (US) 1980-05-20 US disclosed
US-4128658-A HISTAMINE ANTAGONISTS ALLEN & HANBURYS LIMITED (GB) 1978-12-05 US disclosed