Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3567350 | 0.89 | ERN1 (0.48) | TSHRKDM5APABPC1ALDH1A1ERN1 | |
| SCHEMBL14625516 | 0.85 | KDM5A (0.41) | TSHRKDM5APABPC1ALDH1A1LMNA | |
| SCHEMBL3730357 | 0.85 | ERN1 (0.55) | TSHRKDM5APABPC1ALDH1A1ERN1 | |
| SCHEMBL13412750 | 0.85 | ALDH1A1 (0.50) | TSHRKDM5APABPC1ALDH1A1LMNA | |
| SCHEMBL4297093 | 0.82 | ALDH1A1 (0.51) | KDM5AALDH1A1RXFP1CA1CA2 | |
| SCHEMBL3730352 | 0.82 | CXCR2 (0.40) | TSHRKDM5APABPC1ALDH1A1ERN1 | |
| SCHEMBL14458133 | 0.80 | RXFP1 (0.43) | KDM5AALDH1A1RXFP1LMNAHPGD | |
| SCHEMBL1765338 | 0.80 | CXCR2 (0.50) | TSHRALDH1A1ERN1RXFP1LMNA | |
| SCHEMBL31486082 | 0.80 | CXCR2 (0.50) | TSHRALDH1A1ERN1RXFP1LMNA | |
| SCHEMBL14475281 | 0.80 | RXFP1 (0.43) | KDM5AALDH1A1RXFP1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022387-B1 | PROCESS FOR THE PREPARATION OF BENZENE DERIVATIVES BY THE REACTION OF AN ACTIVATED HALOBENZENE WITH AN ORGANIC COMPOUND CONTAINING AN OXYGEN OR SULPHUR ANION | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-01-05 | — | — | EP | disclosed |
| EP-0022387-A1 | Process for the preparation of benzene derivatives by the reaction of an activated halobenzene with an organic compound containing an oxygen or sulphur anion | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-01-14 | — | — | EP | disclosed |