Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.43 |
| ▸ | RELA | Q04206 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31486082 | 1.00 | CXCR2 (0.50) | CXCR2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4297093 | 0.84 | ALDH1A1 (0.51) | CXCR2KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2612359 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14336876 | 0.82 | ERN1 (0.40) | CXCR2KDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL14475281 | 0.82 | RXFP1 (0.43) | CXCR2KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14458133 | 0.82 | RXFP1 (0.43) | CXCR2KDM4EALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL7425418 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7424567 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17540384 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11207914 | 0.80 | TSHR (0.44) | CXCR2KDM4EALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025870-A1 | SYNERGISTIC COMBINATIONS OF THIADIAZOL CARBONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | claimed |
| EP-2061320-A2 | FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES | BASF SE (DE) | 2009-05-27 | — | — | EP | claimed |
| WO-2008095890-A2 | FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES | BASF SE (DE) | 2008-08-14 | — | — | WO | claimed |
| CN-105451559-B | Binary is antifungal and bactericidal conjugate | 拜耳作物科学股份公司 | 2018-01-05 | — | — | CN | disclosed |
| EP-2877028-A1 | COMPOSITIONS AND METHOD OF CONTROLLING PHYTOPARASITIC PEST POPULATIONS | FBSciences Holdings, Inc. (US) | 2015-06-03 | — | — | EP | disclosed |
| WO-2014015134-A1 | COMPOSITIONS AND METHOD OF CONTROLLING PHYTOPARASITIC PEST POPULATIONS | FBSCIENCES HOLDINGS, INC. (US) | 2014-01-23 | — | — | WO | disclosed |
| EP-2642854-A2 | FUNGICIDAL COMPOSITIONS AND METHODS | Bayer Intellectual Property GmbH (DE) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012071520-A2 | FUNGICIDAL COMPOSITIONS AND METHODS | BAYER CROPSCIENCE LP (US) | 2012-05-31 | — | — | WO | disclosed |
| US-20110124501-A1 | Active compound combinations | BAYER CROPSCIENCE AG (DE) | 2011-05-26 | — | — | US | disclosed |
| WO-2011051243-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | disclosed |
| EP-2296467-A2 | METHODS TO CONTROL QOI-RESISTANT FUNGAL PATHOGENS | Dow AgroSciences LLC (US) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009155095-A2 | METHODS TO CONTROL QOI-RESISTANT FUNGAL PATHOGENS | DOW AGROSCIENCES LLC (US) | 2009-12-23 | — | — | WO | disclosed |
| EP-2081900-A2 | NEW N-(3-PYRIDIN-2-YLPROPYL)BENZAMIDE DERIVATIVES | Bayer CropScience SA (FR) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008046838-A2 | N- (3-PYRIDIN-2-YLPROPYL) BENZAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2008-04-24 | — | — | WO | disclosed |
| EP-1885712-A1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE SA (FR) | 2008-02-13 | — | — | EP | disclosed |
| EP-1879878-A2 | NEW HETEROCYCLYLETHYLCARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-01-23 | — | — | EP | disclosed |
| EP-1871744-A1 | NEW HETEROCYCLYLETHYLBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006122955-A1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE SA (FR) | 2006-11-23 | — | — | WO | disclosed |
| WO-2006108791-A2 | HETEROCYCLYLETHYLHETEROCYCLYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2006-10-19 | — | — | WO | disclosed |
| WO-2006108792-A1 | NEW HETEROCYCLYLETHYLBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2006-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124501-A1 | Active compound combinations | CYP51A1, CA4, BROX | CXCR2 3042/4885KDM4E 2182/4885ALDH1A1 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.