2-Mercaptobenzimidazole

2-Mercaptobenzimidazole

SCHEMBL11207938

Sc1nc2ccccc2[nH]1.[Fe]

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
NPC1 O15118 5/20 0.58
RAB9A P51151 5/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
KDM4E B2RXH2 3/20 0.58
PKM P14618 3/20 0.58
NPSR1 Q6W5P4 2/20 0.58
TP53 P04637 2/20 0.58
HSD17B10 Q99714 2/20 0.58
ABCB11 O95342 1/20 0.58
MASP2 O00187 1/20 0.54
MEN1 O00255 1/20 0.54
NUDT1 P36639 1/20 0.54
KMT2A Q03164 1/20 0.54
AOC3 Q16853 1/20 0.54
GAA P10253 2/20 0.50
POLB P06746 2/20 0.48
IDO1 P14902 1/20 0.48
DDAH1 O94760 1/20 0.48
BCHE P06276 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Mercaptobenzimidazole SCHEMBL36857 0.98 ALDH1A1 (0.60) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL29368206 0.98 ALDH1A1 (0.60) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL9355771 0.95 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL8218023 0.95 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL31379735 0.95 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL4911436 0.95 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL10923231 0.95 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL9145547 0.95 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL9145554 0.95 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL11814321 0.95 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113336708-B Metal-mercaptobenzimidazole coordination compound and preparation method and application thereof 苏州大学 2022-12-30 CN claimed
CN-113336708-B Metal-mercaptobenzimidazole coordination compound and preparation method and application thereof 苏州大学 2022-12-30 CN disclosed
CN-113336708-A Metal-mercaptobenzimidazole coordination compound and preparation method and application thereof 苏州大学 2021-09-03 CN disclosed
US-4356274-A METAL SALT OF 2-MERCAPTOBENZOTHIAZOLE OR 2,5-DIMERCAPTO-1,3,4-THIADIAZOLE PENNWALT CORPORATION (US) 1982-10-26 US disclosed