2-Mercaptobenzimidazole

2-Mercaptobenzimidazole

SCHEMBL36857

Sc1nc2ccccc2[nH]1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
NPC1 O15118 5/20 0.60
RAB9A P51151 5/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
KDM4E B2RXH2 3/20 0.60
PKM P14618 3/20 0.60
NPSR1 Q6W5P4 2/20 0.60
TP53 P04637 2/20 0.60
HSD17B10 Q99714 2/20 0.60
ABCB11 O95342 1/20 0.60
MASP2 O00187 1/20 0.56
MEN1 O00255 1/20 0.56
NUDT1 P36639 1/20 0.56
KMT2A Q03164 1/20 0.56
AOC3 Q16853 1/20 0.56
GAA P10253 2/20 0.52
POLB P06746 2/20 0.50
IDO1 P14902 1/20 0.50
DDAH1 O94760 1/20 0.50
BCHE P06276 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Mercaptobenzimidazole SCHEMBL29368206 1.00 ALDH1A1 (0.60) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL8218023 0.98 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL9355771 0.98 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL38652073 0.98 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL11207938 0.98 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL11814321 0.98 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL10923231 0.98 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL9145547 0.98 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL9145554 0.98 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
2-Mercaptobenzimidazole SCHEMBL4911436 0.98 ALDH1A1 (0.58) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 46684 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372755-B1 None US claimed
US-12636259-B2 Transdermal absorption preparation Sumitomo Pharma Co., Ltd. (JP) 2026-05-26 US claimed
CN-122095450-A Electrolytic capacitor 2026-05-26 CN claimed
CN-122080895-A Polyglycolic acid composition and preparation method thereof, biodegradable polyester material and application thereof, and PGA temporary plugging ball and preparation method thereof 2026-05-26 CN claimed
CN-122080540-A Ethylene propylene diene monomer rubber material with high strength and low dynamic ratio and preparation method thereof 2026-05-26 CN claimed
CN-117126500-B Antibacterial runway material and preparation method thereof Hebei xinjinkang plastic products manufacturing Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122085621-A Aqueous stripping liquid, preparation method and application 2026-05-26 CN claimed
US-12630732-B2 Scattering particle, ink composition including the same, and display apparatus including quantum dot layer prepared by using the ink composition SAMSUNG DISPLAY CO., LTD. (KR) 2026-05-19 US claimed
CN-119798128-B Preparation method of dicumyl peroxide 万华化学集团股份有限公司 2026-05-19 CN claimed
CN-122051380-A Application of additive in lithium battery electrolyte, electrolyte and lithium battery 中国科学院大连化学物理研究所 2026-05-15 CN claimed
US-3997346-A Method for stabilizing the image of a thermally developable photosensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-12-14 US claimed
US-3985707-A HEAT AGING RESISTANCE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-10-12 US claimed
US-3979358-A MERCAPTOBENZO-1,3-DIAZOLE, PHENYLENEDIAMINE COMPOUND JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1976-09-07 US claimed
US-3969350-A Base catalysis of azolesulfenamides and sulfur to aminodithioazoles MONSANTO COMPANY (US) 1976-07-13 US claimed
US-3962273-A NOVEL METHOD FOR THE SYNTHESIS OF 4-THIO AND 4-SELENO ETHERS OF 2-PYRAZOLIN-5-ONES EASTMAN KODAK COMPANY (US) 1976-06-08 US claimed
US-3945829-A BINDER, COLLOIDAL SILVER, HETEROCYCLIC MERCAPTO COMPOUND AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) 1976-03-23 US claimed
US-3944695-A Heat printing sheet TOYO SODA MANUFACTURING CO., LTD. (JA) 1976-03-16 US claimed
US-3939056-A Coated plating rack SONY CORPORATION (JA) 1976-02-17 US claimed
US-3936432-A AND SULFUR LIGANDSS- OR O-CONTAINING LIGANDS WITH IMINE OR IMIDAZOLE GROUPS; DITHIOOXAMIDES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-02-03 US claimed
US-3930866-A MAGENTA FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed