Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11698359 | 0.93 | ALDH1A1 (0.41) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL11700318 | 0.90 | ALDH1A1 (0.41) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL4098199 | 0.86 | ALDH1A1 (0.45) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL6207819 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL9641575 | 0.80 | KDM4E (0.44) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL6208798 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL29229215 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL4614388 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL8671460 | 0.71 | KMT2A (0.43) | ALDH1A1HPGDGAAKDM4ESMN1; SMN2 | |
| SCHEMBL7866392 | 0.71 | KMT2A (0.43) | ALDH1A1HPGDGAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327024-A | Iminoisoindolinone pigments, process for their production and use thereof | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |
| US-4317929-A | Tetraphenylketazines and isoindolinone pigments obtained therefrom | CIBA-GEIGY CORPORATION (US) | 1982-03-02 | — | — | US | disclosed |
| US-4314938-A | Iminoisoindolinone pigments containing phenylazoacetoacetyl-aminophenylene groups | CIBA-GEIGY CORPORATION (US) | 1982-02-09 | — | — | US | disclosed |
| US-4231931-A | YELLOW TO RED HUES | CIBA-GEIGY CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4153800-A | Isoindolinone pigments | CIBA-GEIGY CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |
| US-4070367-A | FASTNESS, YELLOW, PLASTICS, LACQUERS, PRINTING INKS | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |
| US-4052410-A | YELLOW, PLASTICS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |
| US-4012370-A | Mono aryl azo-mono-iminoisoindolinone dyestuffs | CIBA-GEIGY CORPORATION (US) | 1977-03-15 | — | — | US | disclosed |
| US-4006162-A | PLASTICS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-3979386-A | YELLOW, COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1976-09-07 | — | — | US | disclosed |
| US-3944547-A | Iminoisoindolinone pigments | CIBA-GEIGY CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |