SCHEMBL4098199

SCHEMBL4098199

COC(=O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1C#N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.45
HPGD P15428 7/20 0.45
GAA P10253 4/20 0.45
MAPT P10636 4/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 2/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
KDM4E B2RXH2 5/20 0.40
HSD17B10 Q99714 3/20 0.40
CASP1 P29466 2/20 0.40
CASP7 P55210 2/20 0.40
MAPK10 P53779 1/20 0.40
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6208798 0.91 ALDH1A1 (0.46) ALDH1A1HPGDGAAMAPTMEN1
SCHEMBL6207819 0.90 ALDH1A1 (0.46) ALDH1A1HPGDGAAMAPTMEN1
SCHEMBL11207965 0.86 ALDH1A1 (0.41) ALDH1A1HPGDGAAMAPTMEN1
SCHEMBL11698359 0.86 ALDH1A1 (0.41) ALDH1A1HPGDGAAMAPTMEN1
SCHEMBL4614388 0.85 ALDH1A1 (0.42) ALDH1A1HPGDGAAMAPTMEN1
SCHEMBL10414166 0.80 ALDH1A1 (0.46) ALDH1A1HPGDGAAMAPTMEN1
SCHEMBL4614147 0.80 ALDH1A1 (0.43) ALDH1A1HPGDGAAMAPTMEN1
SCHEMBL29229215 0.79 ALDH1A1 (0.53) ALDH1A1HPGDGAAMAPTMEN1
SCHEMBL11700318 0.79 ALDH1A1 (0.41) ALDH1A1HPGDGAAMAPTMEN1
SCHEMBL5334826 0.79 CA12 (0.46) ALDH1A1HPGDGAASMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624936-A Process for preparing low viscosity pigments 温州金源新材料科技有限公司 2024-03-01 CN claimed
CN-115073935-A Synthesis method of C.I. pigment orange 61 鞍山市五色石新材料科技有限公司 2022-09-20 CN claimed
CN-110818591-A Preparation method of methyl 3,4,5, 6-tetrachloro-2-cyanobenzoate 彩客化学(沧州)有限公司 2020-02-21 CN claimed
WO-2008096371-A1 ISOINDOLINONE PIGMENTS AND A METHOD OF MANUFACTURING. SUDARSHAN CHEMICAL INDUSTRIES LTD. (IN) 2008-08-14 WO claimed
EP-0668332-A2 Radiation-curable pigmented ink compositions and methods of decorating articles therewith Revlon Consumer Products Corporation (US) 1995-08-23 EP claimed
CN-117624936-A Process for preparing low viscosity pigments 温州金源新材料科技有限公司 2024-03-01 CN disclosed
CN-114196227-B Process for the preparation of isoindolinone pigments 百合花集团股份有限公司 2022-09-30 CN disclosed
CN-115073935-A Synthesis method of C.I. pigment orange 61 鞍山市五色石新材料科技有限公司 2022-09-20 CN disclosed
CN-115073935-A Synthesis method of C.I. pigment orange 61 鞍山市五色石新材料科技有限公司 2022-09-20 CN disclosed
CN-114196227-A Process for the preparation of isoindolinone pigments 百合花集团股份有限公司 2022-03-18 CN disclosed
CN-110818591-A Preparation method of methyl 3,4,5, 6-tetrachloro-2-cyanobenzoate 彩客化学(沧州)有限公司 2020-02-21 CN disclosed
CN-110818591-A Preparation method of methyl 3,4,5, 6-tetrachloro-2-cyanobenzoate 彩客化学(沧州)有限公司 2020-02-21 CN disclosed
US-4043999-A Methyl or methoxy substituted iminoisoindolinone pigments CIBA-GEIGY CORPORATION (US) 1977-08-23 US disclosed
US-4024132-A Azomethine pigments CIBA-GEIGY CORPORATION (US) 1977-05-17 US disclosed
US-4012370-A Mono aryl azo-mono-iminoisoindolinone dyestuffs CIBA-GEIGY CORPORATION (US) 1977-03-15 US disclosed
US-4006162-A PLASTICS, LACQUERS CIBA-GEIGY CORPORATION (US) 1977-02-01 US disclosed
US-3979386-A YELLOW, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1976-09-07 US disclosed
US-3974149-A TONERS CIBA-GEIGY CORPORATION (US) 1976-08-10 US disclosed
US-3971805-A Iminoisoindolinone pigments and process for their manufacture CIBA-GEIGY CORPORATION (US) 1976-07-27 US disclosed
US-3944547-A Iminoisoindolinone pigments CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed