Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 1.00 |
| ▸ | NPC1 | O15118 | 13/20 | 1.00 |
| ▸ | PKM | P14618 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | KLF5 | Q13887 | 3/20 | 0.76 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.74 |
| ▸ | MAOB | P27338 | 1/20 | 0.72 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | MTOR | P42345 | 1/20 | 0.72 |
| ▸ | SCD | O00767 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703736 | 0.89 | NPC1 (0.91) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL22193346 | 0.86 | RAB9A (1.00) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL11706816 | 0.85 | NPC1 (1.00) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL11702938 | 0.85 | NPC1 (0.80) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL11703469 | 0.85 | RAB9A (0.73) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL11703485 | 0.85 | RAB9A (0.73) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL3926899 | 0.84 | NPC1 (1.00) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL11733357 | 0.84 | RAB9A (0.73) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL9728959 | 0.84 | RAB9A (0.72) | RAB9ANPC1PKMMEN1KMT2A | |
| SCHEMBL29263343 | 0.84 | RAB9A (0.76) | RAB9ANPC1PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023889-B1 | IMINOISOINDOLINONE METAL COMPLEXES, PROCESS FOR THEIR MANUFACTURE, METHOD FOR PIGMENTING AN ORGANIC HIGH-MOLECULAR MATERIAL AND HIGH-MOLECULAR ORGANIC MATERIAL CONTAINING SUCH A METAL COMPLEX | CIBA-GEIGY AG (CH) | 1983-03-09 | — | — | EP | disclosed |
| EP-0023889-A1 | Iminoisoindolinone metal complexes, process for their manufacture, method for pigmenting an organic high-molecular material and high-molecular organic material containing such a metal complex | CIBA-GEIGY AG (CH) | 1981-02-11 | — | — | EP | disclosed |
| US-4011236-A | N-(BENZIMIDAZOL-2-YL)ARYLCARBOXAMIDES AS ULTRAVIOLET (UV) LIGHT ABSORBERS | MERCK & CO., INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-4009164-A | Novel 2-substituted-1,2,4-thiadiazole-[2,3-a]-benzimidazoles and process for their preparation | SYNTEX (U.S.A.) INC. (US) | 1977-02-22 | — | — | US | disclosed |
| US-3976654-A | FUNGICIDE | SYNTEX (U.S.A.) INC. (US) | 1976-08-24 | — | — | US | disclosed |
| US-3946031-A | FUNGICIDES | SYNTEX INC. (US) | 1976-03-23 | — | — | US | disclosed |