Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.72 |
| ▸ | NPC1 | O15118 | 8/20 | 0.72 |
| ▸ | PKM | P14618 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728922 | 0.86 | NPC1 (0.70) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL9728941 | 0.86 | NPC1 (0.67) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL11207978 | 0.84 | RAB9A (1.00) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL30387611 | 0.84 | NPC1 (0.70) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL9729182 | 0.84 | NPC1 (0.70) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL9728665 | 0.78 | NPC1 (0.57) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL7456210 | 0.77 | LMNA (0.65) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL9728483 | 0.77 | SMN1; SMN2 (0.68) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL6257175 | 0.77 | KMT2A (0.69) | RAB9ANPC1PKMKMT2AMEN1 | |
| SCHEMBL9729002 | 0.76 | ALPL (0.51) | RAB9ANPC1PKMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |