Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209018 | 0.86 | HIF1A (0.42) | HIF1AMEN1KMT2ATSHRCHRM3 | |
| SCHEMBL11210963 | 0.81 | HIF1A (0.52) | HIF1AMEN1KMT2ANPC1RAB9A | |
| Bromide SCHEMBL11206144 | 0.81 | HIF1A (0.39) | HIF1AMEN1KMT2ARAB9ATSHR | |
| SCHEMBL11205449 | 0.76 | TSHR (0.47) | HIF1AKMT2ATSHR | |
| SCHEMBL11209786 | 0.74 | CYP3A4 (0.64) | HIF1AMEN1KMT2ATSHRCHRM3 | |
| SCHEMBL11209847 | 0.73 | HIF1A (0.41) | HIF1A | |
| SCHEMBL11207790 | 0.73 | HTR1F (0.39) | MEN1KMT2ATSHR | |
| SCHEMBL11208075 | 0.73 | CYP3A4 (0.44) | HIF1ATSHRVKORC1 | |
| SCHEMBL11206692 | 0.73 | CHRM2 (0.59) | HIF1AMEN1KMT2ATSHRNPSR1 | |
| Bromide SCHEMBL11210620 | 0.72 | CHRM2 (0.58) | HIF1AMEN1KMT2ATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094833-A2 | Novel 1,2-benzisoxazole derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1983-11-23 | — | — | EP | disclosed |