Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11210539 | 0.97 | HTR1F (0.38) | HTR1FHTR2ADRD3HTR1AFAAH | |
| SCHEMBL11209018 | 0.86 | HIF1A (0.42) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL11207375 | 0.85 | SLC6A3 (0.50) | HTR2ADRD3FAAHSLC6A3 | |
| SCHEMBL11211029 | 0.83 | FAAH (0.41) | FAAHKMT2ASLC6A3HTR3A | |
| Bromide SCHEMBL10923172 | 0.74 | MAPT (0.46) | HTR1FHTR2ADRD3HTR1AFAAH | |
| SCHEMBL11207995 | 0.73 | HIF1A (0.43) | KMT2AMEN1TSHR | |
| SCHEMBL10920458 | 0.71 | MEN1 (0.40) | HTR2AKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL10919126 | 0.71 | MEN1 (0.40) | HTR2AKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7271094 | 0.71 | FAAH (0.47) | HTR2ADRD3FAAHHTR3A | |
| Hydrochloric Acid SCHEMBL7271028 | 0.70 | FAAH (0.46) | HTR2ADRD3FAAHHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094833-A2 | Novel 1,2-benzisoxazole derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1983-11-23 | — | — | EP | disclosed |