Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203768 | 0.87 | CYP4F2 (0.44) | ALOX5ALDH1A1 | |
| SCHEMBL7641739 | 0.85 | ALOX5 (0.61) | ALOX5GLAKMT2AF2RL1ALDH1A1 | |
| SCHEMBL11210323 | 0.84 | MAPT (0.47) | ALOX5KMT2APOLB | |
| SCHEMBL11039007 | 0.84 | ALDH1A1 (0.44) | ALOX5ALDH1A1POLB | |
| SCHEMBL11133561 | 0.84 | ALOX5 (0.53) | ALOX5KMT2AALDH1A1 | |
| SCHEMBL1239542 | 0.82 | ALOX5 (0.65) | ALOX5GLAKMT2AF2RL1ALDH1A1 | |
| SCHEMBL445381 | 0.82 | ALOX5 (0.60) | ALOX5KMT2AF2RL1ALDH1A1CALM1 | |
| SCHEMBL7692787 | 0.82 | HTT (0.51) | GLAKMT2AALDH1A1POLB | |
| SCHEMBL7642711 | 0.81 | ALOX5 (0.56) | ALOX5GLAKMT2AF2RL1ALDH1A1 | |
| SCHEMBL11203911 | 0.79 | ALOX5 (0.53) | ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349699-B | Synthesis method of (R) -2- (4-methoxybenzyl) -4-methylene-1-p-toluenesulfonyl pyrrolidine | 叶艳影 | 2024-05-03 | — | — | CN | claimed |
| CN-114349699-A | Synthesis method of (R) -2- (4-methoxybenzyl) -4-methylene-1-p-toluenesulfonyl pyrrolidine | 叶艳影 | 2022-04-15 | — | — | CN | claimed |
| CN-114349699-B | Synthesis method of (R) -2- (4-methoxybenzyl) -4-methylene-1-p-toluenesulfonyl pyrrolidine | 叶艳影 | 2024-05-03 | — | — | CN | disclosed |
| CN-114349699-A | Synthesis method of (R) -2- (4-methoxybenzyl) -4-methylene-1-p-toluenesulfonyl pyrrolidine | 叶艳影 | 2022-04-15 | — | — | CN | disclosed |
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |