Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601983 | 0.86 | ATM (0.58) | ALDH1A1HPGDRAB9ANPC1MCL1 | |
| SCHEMBL1478030 | 0.86 | ATM (0.58) | ALDH1A1HPGDRAB9ANPC1MCL1 | |
| SCHEMBL14640957 | 0.84 | MCL1 (0.63) | ALDH1A1HSD17B10HPGDKDM4ELMNA | |
| SCHEMBL11208180 | 0.84 | RAB9A (0.47) | ALDH1A1HSD17B10HPGDKDM4ERAB9A | |
| SCHEMBL11212981 | 0.84 | PDK2 (0.45) | ALDH1A1HSD17B10MAPK1HPGDKDM4E | |
| SCHEMBL14447018 | 0.81 | MRGPRX4 (0.51) | ALDH1A1HSD17B10MAPK1HPGDKDM4E | |
| SCHEMBL11219368 | 0.81 | MCL1 (0.55) | ALDH1A1HSD17B10MAPK1HPGDKDM4E | |
| SCHEMBL11525514 | 0.81 | L3MBTL1 (0.65) | ALDH1A1HPGDLMNARAB9ANPC1 | |
| SCHEMBL22542335 | 0.80 | HPGD (0.63) | ALDH1A1HSD17B10MAPK1HPGDKDM4E | |
| SCHEMBL13459471 | 0.80 | HPGD (0.44) | ALDH1A1HSD17B10MAPK1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |