SCHEMBL11208299

SCHEMBL11208299

CN1C=C/C(=C/[N+](=O)[O-])c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.43
MAPT P10636 5/20 0.43
KMT2A Q03164 5/20 0.43
ALDH1A1 P00352 4/20 0.43
NPSR1 Q6W5P4 3/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
HTT P42858 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 2/20 0.43
POLB P06746 1/20 0.43
BLM P54132 1/20 0.43
MCL1 Q07820 1/20 0.43
MAPK1 P28482 3/20 0.33
THRB P10828 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TTR P02766 2/20 0.33
PKM P14618 1/20 0.33
TRPA1 O75762 1/20 0.32
MTOR P42345 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11208303 1.00 MEN1 (0.43) MEN1MAPTKMT2AALDH1A1NPSR1
SCHEMBL10625407 0.79 MAPT (0.46) MEN1MAPTKMT2AALDH1A1NPSR1
SCHEMBL10625415 0.79 MAPT (0.46) MEN1MAPTKMT2AALDH1A1NPSR1
SCHEMBL13061952 0.76 MAPT (0.49) MEN1MAPTKMT2AALDH1A1NPSR1
SCHEMBL11592985 0.73 ALDH1A1 (0.45) MEN1MAPTKMT2AALDH1A1NPSR1
SCHEMBL11592988 0.73 ALDH1A1 (0.45) MEN1MAPTKMT2AALDH1A1NPSR1
SCHEMBL11591023 0.70 ALDH1A1 (0.42) MEN1MAPTKMT2AALDH1A1NPSR1
SCHEMBL1906045 0.70 ALDH1A1 (0.43) MEN1MAPTKMT2AALDH1A1NPSR1
SCHEMBL11588389 0.70 ALDH1A1 (0.43) MEN1MAPTKMT2AALDH1A1NPSR1
SCHEMBL16381637 0.67 TRPA1 (0.56) MEN1MAPTKMT2AALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0012020-B1 DRY SILVER PHOTO-SENSITIVE COMPOSITIONS, DYES FOR USE THEREIN AND PREPARATION OF SUCH DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-01-26 EP disclosed
US-4316984-A Thermolabile acutance dyes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-02-23 US disclosed
US-4260676-A NITRO-SUBSTITUTED DYES FOR USE IN PHOTOSENSITIVE COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-04-07 US disclosed
WO-1980001213-A1 DRY SILVER PHOTO-SENSITIVE COMPOSITIONS,DYES FOR USE THEREIN AND PREPARATION OF SUCH DYES MINNESOTA MINING & MFG (GB) 1980-06-12 WO disclosed
EP-0012020-A1 Dry silver photo-sensitive compositions, dyes for use therein and preparation of such dyes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-06-11 EP disclosed