Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11276213 | 0.99 | ADRB2 (0.45) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL11271082 | 0.86 | PBRM1 (0.46) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11264396 | 0.85 | F2 (0.46) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL11208118 | 0.78 | ALDH1A1 (0.52) | ADRB2ADRB1ADRB3ALDH1A1LMNA | |
| SCHEMBL12099223 | 0.76 | PBRM1 (0.45) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL12163002 | 0.76 | PBRM1 (0.45) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL12099224 | 0.76 | PBRM1 (0.45) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL9254112 | 0.76 | PBRM1 (0.55) | ADRB2ADRB1ADRB3ALDH1A1KDM4E | |
| SCHEMBL27654141 | 0.74 | SMN1; SMN2 (0.51) | ALDH1A1KDM4EPBRM1NPC1LMNA | |
| SCHEMBL9041395 | 0.74 | PBRM1 (0.53) | ADRB2ADRB1ADRB3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344957-A | Benz-acyl-benzimidazole derivatives and antiallergic compositions | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |
| US-4322431-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-4213993-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| US-4141982-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |