Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204786 | 0.84 | LMNA (0.64) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL8717010 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL10866412 | 0.83 | DHODH (0.67) | KDM4EALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL15483449 | 0.82 | KDM4E (0.73) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL8321362 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL1898810 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL10948402 | 0.77 | KDM4E (0.77) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL2799473 | 0.77 | DHODH (0.57) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL21799199 | 0.76 | MAPT (0.67) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL10610649 | 0.76 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027891-B1 | AMMONIUM SALTS, A PROCESS FOR THE PREPARATION OF AMINES UNDERLYING THESE, AND COATING COMPOSITIONS ON THE BASIS OF MANUFACTURED POLYURETHANE OR EPOXY RESIN PRODUCTS WHICH CONTAIN THE AMMONIUM SALTS | BAYER AG (DE) | 1983-03-09 | — | — | EP | disclosed |
| EP-0027891-A1 | Ammonium salts, a process for the preparation of amines underlying these, and coating compositions on the basis of manufactured polyurethane or epoxy resin products which contain the ammonium salts | BAYER AG (DE) | 1981-05-06 | — | — | EP | disclosed |