Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321362 | 0.96 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL8324533 | 0.86 | MEN1 (0.55) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8327199 | 0.84 | KDM4E (0.74) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL11208353 | 0.83 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL8321360 | 0.81 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10POLBMEN1 | |
| SCHEMBL8687997 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL8322442 | 0.77 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10MAPK1TDP1 | |
| SCHEMBL8326754 | 0.75 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL8326990 | 0.73 | RAB9A (0.53) | KDM4EALDH1A1HSD17B10POLBMEN1 | |
| SCHEMBL8324531 | 0.71 | MEN1 (0.77) | KDM4EALDH1A1HSD17B10MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693478-B1 | Quinoline compounds | GREEN CROSS CORP (JP) | 1998-08-12 | — | — | EP | claimed |