SCHEMBL11208418

SCHEMBL11208418

Cc1cccc(Cc2ccccc2Cc2ccccc2)c1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.48
CALM1 P0DP23 1/20 0.44
BCL2 P10415 1/20 0.42
BCL2L1 Q07817 1/20 0.42
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C19 P33261 2/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
CNR2 P34972 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
LDHA P00338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276090 0.96 CALM1 (0.48) HTR2ACALM1BCL2BCL2L1CYP3A4
Ammonia Solution, Strong SCHEMBL27502158 0.94 CALM1 (0.46) HTR2ACALM1BCL2BCL2L1CYP3A4
Chloromethane SCHEMBL27508976 0.92 CALM1 (0.44) HTR2ACALM1BCL2BCL2L1CYP3A4
Hydrochloric Acid SCHEMBL28173092 0.92 CALM1 (0.44) HTR2ACALM1BCL2BCL2L1CYP3A4
SCHEMBL11202919 0.87 TAAR1 (0.45) CYP3A4CYP2C19TSHRCNR2GPR55
SCHEMBL7861886 0.87 CALM1 (0.52) HTR2ACALM1BCL2BCL2L1CYP3A4
SCHEMBL3306785 0.87 ESR1 (0.47) CYP3A4CYP2C19TSHRSMN1; SMN2CNR2
SCHEMBL29946842 0.85 CYP3A4 (0.41) HTR2ACALM1CYP3A4CYP2D6CYP2C19
SCHEMBL2140999 0.85 HTR2A (0.54) HTR2ACALM1BCL2BCL2L1CYP3A4
SCHEMBL7192027 0.85 HTR2A (0.54) HTR2ACALM1BCL2BCL2L1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4371726-A Composition suitable for mechanical power transmission and process for operating traction drives NIPPON STEEL CHEMICAL CO., LTD. (JP) 1983-02-01 US disclosed