Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546855 | 0.93 | TAAR1 (0.46) | ESR1ESR2TRPA1ATMGPR84 | |
| SCHEMBL11202919 | 0.91 | TAAR1 (0.45) | ESR1ESR2TRPA1ATMGPR84 | |
| SCHEMBL6546715 | 0.89 | GABRA1 (0.48) | ESR1ESR2TRPA1ATMGPR84 | |
| SCHEMBL11208418 | 0.87 | HTR2A (0.48) | ESR1ESR2CYP1A2TSHRCYP3A4 | |
| SCHEMBL6546223 | 0.87 | GABRA1 (0.46) | ESR1ESR2TRPA1ATMGPR84 | |
| SCHEMBL1276090 | 0.85 | CALM1 (0.48) | ESR1ESR2CYP1A2TSHRCYP3A4 | |
| SCHEMBL19335777 | 0.85 | ACHE (0.48) | ESR1ESR2TP53MAPTTAAR1 | |
| SCHEMBL1834878 | 0.85 | HSPA5 (0.64) | ESR1ESR2TRPA1ATMTP53 | |
| SCHEMBL6546102 | 0.85 | TAAR1 (0.41) | ESR1ESR2TRPA1ATMGPR84 | |
| SCHEMBL11192895 | 0.85 | MEN1 (0.48) | TAAR1P2RX7SMN1; SMN2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | claimed |
| US-20100292510-A1 | PROCESS FOR PREPARING CYCLOALIPHATIC AMINES | BASF SE (DE) | 2010-11-18 | — | — | US | claimed |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | claimed |
| EP-0502387-B1 | Process for producing 3,3',4,4'-tetramethyldiphenylmethane | MITSUBISHI GAS CHEMICAL CO (JP) | 1995-04-26 | — | — | EP | claimed |
| US-5254768-A | Catalytic isomerization | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1993-10-19 | — | — | US | claimed |
| EP-0502387-A1 | Process for producing 3,3',4,4'-tetramethyldiphenylmethane | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-09-09 | — | — | EP | claimed |
| EP-0281784-A1 | Perfluoro-1,1-di(orthoxylyl) alkyl compounds | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1988-09-14 | — | — | EP | claimed |
| JP-4275241-A | — | — | None | — | — | JP | disclosed |
| CN-118235091-A | Transfer film, laminate having conductor pattern, method for producing laminate having conductor pattern, and method for producing transfer film | 富士胶片株式会社 | 2024-06-21 | — | — | CN | disclosed |
| US-11724978-B2 | Method for oxidizing a 1,1,-bis-(3,4-dimethylphenyl)-alkane to 3,3′,4,4′-benzophenone tetracarboxylic acid | EVONIK FIBRES GMBH (AT) | 2023-08-15 | — | — | US | disclosed |
| EP-3838883-B1 | METHOD FOR OXIDIZING A 1,1-BIS-(3,4-DIMETHYLPHENYL)-ALKANE TO 3,3',4,4'-BENZOPHENONE TETRACARBOXYLIC ACID | EVONIK FIBRES GMBH (AT) | 2023-07-12 | — | — | EP | disclosed |
| CN-113929866-B | Modified resin and resin composition | 旭化成株式会社 | 2023-07-07 | — | — | CN | disclosed |
| CN-115121263-A | Solid acid catalyst and preparation method and application thereof | 华东理工大学 | 2022-09-30 | — | — | CN | disclosed |
| EP-0125342-A1 | Process for preparation of aromatic polycarboxylic acids and intermediates therefor | THE UPJOHN COMPANY (US) | 1984-11-21 | — | — | EP | disclosed |
| US-4384871-A | Dyestuff-containing microscopic capsule dispersion for record materials | MITSUI TOATSU CHEMICALS, INC. (JP) | 1983-05-24 | — | — | US | disclosed |
| EP-0007694-B1 | PROCESS FOR PREPARING 3,4,3'4'-BENZOPHENONE-TETRACARBOXYLIC DIANHYDRIDE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1983-04-06 | — | — | EP | disclosed |
| EP-0058430-A1 | Dyestuff-containing microscopic capsule dispersion for record materials | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1982-08-25 | — | — | EP | disclosed |
| WO-1980000149-A1 | PROCESS FOR PREPARING 3,4,3',4'-BENZOPHENONETETRA-CARBOXYLIC DIANHYDRIDE | GULF RESEARCH DEVELOPMENT CO (US) | 1980-02-07 | — | — | WO | disclosed |
| EP-0007694-A1 | Process for preparing 3,4,3'4'-benzophenone-tetracarboxylic dianhydride | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-02-06 | — | — | EP | disclosed |
| US-4173573-A | Process for preparing 3,4,3,4-benzophenone-tetracarboxylic dianhydride | GULF RESEARCH AND DEVELOPMENT COMPANY (US) | 1979-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | CACNA1B, CACNA1C, ORAI1 | ESR1 4432/4885ESR2 3398/4885TRPA1 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.