Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56957 | 0.80 | GABRA1 (0.64) | GABRA1GABRB2GABRB1GABRG2GABRB3 | |
| SCHEMBL7745836 | 0.80 | GABRA1 (0.64) | GABRA1GABRB2GABRB1GABRG2GABRB3 | |
| SCHEMBL13640241 | 0.75 | GABRA1 (0.57) | GABRA1GABRB2GABRB1GABRG2GABRB3 | |
| SCHEMBL4912818 | 0.74 | GABRA1 (0.61) | GABRA1GABRB2GABRB1GABRG2GABRB3 | |
| SCHEMBL13583692 | 0.74 | GABRA1 (0.55) | GABRA1GABRB2GABRB1GABRG2GABRB3 | |
| SCHEMBL10775084 | 0.72 | GABRA1 (0.53) | GABRA1GABRB2GABRB1GABRG2GABRB3 | |
| Propofol SCHEMBL36245 | 0.72 | GABRA1 (1.00) | GABRA1GABRB2GABRB1GABRG2GABRB3 | |
| Propofol SCHEMBL2414429 | 0.72 | GABRA1 (1.00) | GABRA1GABRB2GABRB1GABRG2GABRB3 | |
| SCHEMBL4912333 | 0.71 | GABRA1 (0.57) | GABRA1GABRB2GABRB1GABRG2GABRB3 | |
| Propofol SCHEMBL9016525 | 0.71 | GABRA1 (0.85) | GABRA1GABRB2GABRB1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005053-B1 | FLAME-RETARDANT ORGANIC PHOSPHATES, THEIR PRODUCTION, AND COMPOSITIONS CONTAINING THEM | FMC Corporation (US) | 1983-05-25 | — | — | EP | disclosed |
| EP-0012340-B1 | SELF-EXTINGUISHING THERMOPLASTIC MOULDING COMPOSITIONS AND SHAPED ARTICLES MADE THEREFROM | BASF Aktiengesellschaft (DE) | 1983-03-16 | — | — | EP | disclosed |
| US-4246169-A | Flammable plastics containing a flame retardant amount of polyarylphosphates and the polyarylphosphates | FMC CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| EP-0012340-A1 | Self-extinguishing thermoplastic moulding compositions and shaped articles made therefrom | BASF Aktiengesellschaft (DE) | 1980-06-25 | — | — | EP | disclosed |
| EP-0005053-A2 | Flame-retardant organic phosphates, their production, and compositions containing them | FMC Corporation (US) | 1979-10-31 | — | — | EP | disclosed |