Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030908 | 0.98 | PDE4A (0.46) | PDE4AGAATDP1RAB9ALMNA | |
| SCHEMBL11156838 | 0.98 | PDE4A (0.46) | PDE4AGAATDP1RAB9ALMNA | |
| SCHEMBL11257183 | 0.78 | PDE4A (0.46) | PDE4AKMT2A | |
| SCHEMBL11263452 | 0.77 | PDE4A (0.49) | PDE4AGAARAB9A | |
| SCHEMBL11030790 | 0.76 | HRH4 (0.33) | SMN1; SMN2 | |
| SCHEMBL11261008 | 0.76 | LMNA (0.42) | PDE4AGAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL11261428 | 0.74 | NPSR1 (0.44) | PDE4AGAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL11270441 | 0.74 | LMNA (0.41) | PDE4AGAALMNASMN1; SMN2MEN1 | |
| SCHEMBL11249913 | 0.74 | NPSR1 (0.44) | PDE4AGAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL10943810 | 0.71 | TSHR (0.35) | TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4380609-A | Prevulcanization inhibitors of thio-triazine-amines for rubber | MONSANTO COMPANY (US) | 1983-04-19 | — | — | US | disclosed |