Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | CASP14 | P31944 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP5 | P51878 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3296576 | 0.82 | PDE4A (0.64) | PDE4AKDM4EGAACTSKCTSS | |
| SCHEMBL11156838 | 0.79 | PDE4A (0.46) | PDE4AGAARAB9A | |
| SCHEMBL11030908 | 0.79 | PDE4A (0.46) | PDE4AGAARAB9A | |
| SCHEMBL11257183 | 0.79 | PDE4A (0.46) | PDE4A | |
| SCHEMBL11208560 | 0.77 | PDE4A (0.43) | PDE4AGAARAB9A | |
| SCHEMBL11263187 | 0.75 | PDE4A (0.50) | PDE4AKDM4EGAACTSKCTSS | |
| SCHEMBL11249913 | 0.75 | NPSR1 (0.44) | PDE4AKDM4EGAANPSR1RAB9A | |
| SCHEMBL11261428 | 0.75 | NPSR1 (0.44) | PDE4AKDM4EGAANPSR1RAB9A | |
| SCHEMBL11270441 | 0.75 | LMNA (0.41) | PDE4AGAANPSR1 | |
| SCHEMBL11030790 | 0.73 | HRH4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339577-A | CROSSLINKING INHIBITORS FOR RUBBERS | MONSANTO COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4301260-A | Vulcanizable rubber compositions scorch inhibited by 2-(thioamino)-4,6-diamino-1,3,5-triazines | MONSANTO COMPANY (US) | 1981-11-17 | — | — | US | disclosed |